Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Hiroshi Ueda, Johan Bøtker, Magnus Edinger, Korbinian Löbmann, Holger Grohganz, Anette Müllertz, Thomas Rades, Jesper Østergaard
Topics & Concepts
NapNaproxen SodiumAmorphous solidDissolutionSolubilityNaproxenChemistryCrystallizationRaman spectroscopyChemical engineeringAnalytical Chemistry (journal)Materials scienceOrganic chemistryNeuroscienceMedicineOpticsPhysicsBiologyPathologyEngineeringAlternative medicineDrug Solubulity and Delivery SystemsAnalytical Methods in PharmaceuticalsAnalytical Chemistry and Chromatography