Cytokinin Inhibits Fungal Development and Virulence by Targeting the Cytoskeleton and Cellular Trafficking
Rupali Gupta, Gautam Anand, Lorena Pizarro, Dana Laor Bar‐Yosef, Neta Kovetz, Noa Sela, Tal Yehuda, Ehud Gazit, Maya Bar
Abstract
likely recognizes CK and responds to it, resulting in cell cycle and individual cell growth retardation, via downregulation of cytoskeletal components and endocytic trafficking. Mutant analyses in yeast confirmed that the endocytic pathway is a CK target. Our work demonstrates a conserved role for CK in yeast and fungal biology, suggesting that pathogen-host interactions may cause molecular adaptations in fundamental processes in eukaryotic biology.
Topics & Concepts
Endomembrane systemBiologyCell biologyEndocytic cycleCytokininEndocytosisBotrytis cinereaESCRTVirulenceCellBotanyIntracellularGeneGeneticsEndosomeAuxinGolgi apparatusEndoplasmic reticulumPlant Reproductive BiologyFungal Plant Pathogen ControlPlant-Microbe Interactions and Immunity