A new antidiabetic and anti-inflammatory biflavonoid from <i>Schinus polygama</i> (Cav.) Cabrera leaves
Heba A. S. El‐Nashar, Nada M. Mostafa, Omayma A. Eldahshan, Abdel Nasser B. Singab
Abstract
A new biflavonoid, luteolin-(6→8'')-apigenin was isolated from 80% methanol extract of Schinus polygama (Cav.) Cabrera leaves (Anacardiaceae). The structure was elucidated by 1D and 2D-NMR spectroscopic data. This compound exhibited in vitro antidiabetic effect via α-amylase assay. Furthermore, it possesses anti-inflammatory activity through membrane stabilization effect on erythrocytes.
Topics & Concepts
AnacardiaceaeChemistryTraditional medicineApigeninLuteolinIn vitroThymelaeaceaeFlavonoidBotanyBiochemistryBiologyAntioxidantMedicineBioactive natural compoundsPhytochemicals and Medicinal PlantsNatural Antidiabetic Agents Studies