Litcius/Paper detail

Enhancer dynamics: Unraveling the mechanism of transcriptional bursting

Takashi Fukaya

2023Science Advances27 citationsDOIOpen Access PDF

Abstract

Transcriptional bursting is a prevalent feature of gene expression. The transient assembly of transcription factor clusters at regulatory DNAs is critical to control bursting dynamics.

Topics & Concepts

BurstingEnhancerDynamics (music)Mechanism (biology)Transcription factorRegulation of gene expressionBiologyGene expressionTranscription (linguistics)GeneComputational biologyGeneticsCell biologyNeurosciencePhysicsPhilosophyQuantum mechanicsAcousticsLinguisticsGenomics and Chromatin DynamicsRNA Research and SplicingDNA and Nucleic Acid Chemistry