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Betulin, an active component from Chinese herb birch bark, suppresses tumor angiogenesis and tumor growth by inhibiting the PAX2/VEGF-A/VEGR2 signaling pathway in non-small cell lung cancer

Zhan Li, Manting Huang, Jiaying Wang, Jinru Lin, Quantan Wu, Pu Wang, Shanggui Zhuo, Weisong Zhang, Zhiling Liu, Qiudi Deng, Xiyong Yu, Xueping Lei

2025Phytomedicine5 citationsDOI

Topics & Concepts

Cancer researchAngiogenesisLung cancerHerbSignal transductionChemistryMedicinePharmacologyTumor cellsCell growthSignal pathwayCancerBetulinNeovascularizationSignalling pathwaysCellLungChinese herbsTissue remodelingMedicinal herbsComponent (thermodynamics)CarcinogenesisNatural product bioactivities and synthesisPhytochemical Studies and BioactivitiesMedicinal Plant Pharmacodynamics Research
Betulin, an active component from Chinese herb birch bark, suppresses tumor angiogenesis and tumor growth by inhibiting the PAX2/VEGF-A/VEGR2 signaling pathway in non-small cell lung cancer | Litcius