Litcius/Paper detail

Translation of the poly(GR) frame in C9ORF72-ALS/FTD is regulated by cis-elements involved in alternative splicing

Alexa A. Lampasona, Sandra Almeida, Fen‐Biao Gao

2021Neurobiology of Aging16 citationsDOIOpen Access PDF

Topics & Concepts

C9orf72RNA splicingTrinucleotide repeat expansionPoly(A)-binding proteinTranslation (biology)IntronBiologyOpen reading frameRNAGeneticsFrontotemporal dementiaRNA-binding proteinMolecular biologyMessenger RNAGenePeptide sequenceMedicineDementiaAlleleDiseasePathologyAmyotrophic Lateral Sclerosis ResearchRNA Research and SplicingNeurogenetic and Muscular Disorders Research