The dynamics of γ-secretase and its substrates
Manuel Hitzenberger, Alexander Götz, Simon Menig, Barbara Brunschweiger, Martin Zacharias, Christina Scharnagl
Topics & Concepts
ProteolysisBiologyAmyloid precursor protein secretaseTransmembrane proteinBiophysicsAmyloid precursor proteinTransmembrane domainProteaseConformational changeBiochemistryCell biologyEnzymeMembraneReceptorAlzheimer's diseaseMedicinePathologyDiseaseAlzheimer's disease research and treatmentsLipid Membrane Structure and BehaviorCellular transport and secretion