A novel homozygous variant in ZP2 causes abnormal zona pellucida formation and female infertility
Yiming Sun, Yang Zeng, Hua Chen, Zhou Zhou, Jing Fu, Qing Sang, Lei Wang, Xiaoxi Sun, Biaobang Chen, Congjian Xu
Topics & Concepts
Zona pellucidaSanger sequencingBiologyFrameshift mutationGeneticsZona pellucida glycoproteinPhenotypeInfertilityExome sequencingChinese hamster ovary cellMutantMutationMolecular biologyOocyteGeneEmbryoCell culturePregnancySkin and Cellular Biology ResearchGenetic Syndromes and ImprintingHair Growth and Disorders