Transcriptome analysis using patient iPSC-derived skeletal myocytes: Bet1L as a new molecule possibly linked to neuromuscular junction degeneration in ALS
Eileen M. Lynch, Samantha Robertson, Claire FitzGibbons, Megan Reilly, Colton Switalski, Adam Eckardt, Sin-Ruow Tey, Koji Hayakawa, Masatoshi Suzuki
Topics & Concepts
Amyotrophic lateral sclerosisNeuromuscular junctionBiologySkeletal muscleInduced pluripotent stem cellTARDBPSOD1C9orf72MyocyteCell biologyMyopathyNeurosciencePathologyGeneticsMedicineEndocrinologyGeneTrinucleotide repeat expansionDiseaseEmbryonic stem cellAlleleAmyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells ResearchNeurogenetic and Muscular Disorders Research