<i>In vivo</i> self-assembled shape-memory polyurethane for minimally invasive delivery and therapy
Shifen Li, Hua Zhang, Jieqi Xie, Zhaoyi Wang, Kai Wang, Zihe Zhai, Jie Ding, Shuqin Wang, Liyin Shen, Jun Wen, Yida Tang, Huanan Wang, Yang Zhu, Changyou Gao
Abstract
, which could efficiently overcome the limited-size problem within MIS and meet a larger treatment area. The diselenide bonds in the PCLUSe cardiac patches protected the myocardium under oxidative stress post myocardial infarction (MI), and significantly maintained the cardiac functions.
Topics & Concepts
PolyurethaneMaterials scienceIn vivoBiomedical engineeringDiselenideShape-memory alloyNanotechnologyFabricationElastomerMedicineComposite materialPathologyBiologyMetallurgySeleniumAlternative medicineBiotechnologyPolymer composites and self-healingElectrospun Nanofibers in Biomedical ApplicationsBone Tissue Engineering Materials