Levomilnacipran Improves Lipopolysaccharide-Induced Dysregulation of Synaptic Plasticity and Depression-Like Behaviors via Activating BDNF/TrkB Mediated PI3K/Akt/mTOR Signaling Pathway
Yuhan Wu, Zhanpeng Zhu, Tian Lan, Shuhan Li, Ye Li, Changmin Wang, Yabo Feng, Xueqin Mao, Shuyan Yu
Topics & Concepts
Tropomyosin receptor kinase BPI3K/AKT/mTOR pathwaySynaptic plasticityProtein kinase BAntidepressantNeuroinflammationNeuroscienceHippocampusMedicineInternal medicinePsychologyNeurotrophic factorsPhosphorylationSignal transductionBiologyCell biologyReceptorInflammationTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms