Photochemistry of P,N-bidentate rhenium(<scp>i</scp>) tricarbonyl complexes: reactive species generation and potential application for antibacterial photodynamic therapy
Alison Acosta, Javier Antipán, Mariano Fernández, Gaspar Prado, Catalina Sandoval‐Altamirano, Germán Günther, Izabook Gutiérrez‐Urrutia, Ignacio Poblete‐Castro, Andrés Vega, Nancy Pizarro
Abstract
in irradiated solutions of the compounds, which follows the same tendency as their singlet oxygen generation quantum yield: RePNBr > RePNTfO > RePNNBr, while no antibacterial activity is observed in the darkness. This result indicates that the generation of singlet oxygen plays a key role in the antibacterial capacity of these complexes.
Topics & Concepts
Photodynamic therapyRheniumChemistryDenticityMedicinal chemistryCombinatorial chemistryOrganic chemistryMetalNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesPorphyrin and Phthalocyanine Chemistry