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Overexpression of HOTAIR attenuates Pi-induced vascular calcification by inhibiting Wnt/β-catenin through regulating miR-126/Klotho/SIRT1 axis

Yan Chen, Chong Huang, Shuying Zhu, Zou Hong-chang, Chengyun Xu, Yan-Xia Chen

2021Molecular and Cellular Biochemistry32 citationsDOI

Topics & Concepts

Wnt signaling pathwayKlothoHOTAIRGene knockdownCalcificationCancer researchChemistryCell biologySignal transductionVascular smooth muscleBiologyDownregulation and upregulationEndocrinologyInternal medicineMedicineBiochemistryApoptosisKidneySmooth muscleLong non-coding RNAGeneParathyroid Disorders and TreatmentsGenetic Syndromes and ImprintingMicroRNA in disease regulation
Overexpression of HOTAIR attenuates Pi-induced vascular calcification by inhibiting Wnt/β-catenin through regulating miR-126/Klotho/SIRT1 axis | Litcius