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Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-(Imine-Thiazole)-Cu(OAc)<sub>2</sub> nanocomposite catalyzed one-pot three-component synthesis of 2-Substituted benzothiazoles using S<sub>8</sub> as sulfur source

Indrajit Patra, Mustafa M. Kadhim, Hamzah H. Kzar, Yasser Fakri Mustafa, Huda Ahmed Jameel

2022Journal of Sulfur Chemistry15 citationsDOI

Abstract

Cu (OAc)2 was immobilized on the surface of magnetic nanoparticles modified by Imine-Thiazole acting as a ligand. This immobilization is done to fabricate a new and green magnetically recoverable copper catalyst [Fe3O4@SiO2-(Imine-Thiazole)-Cu (OAc)2]. Techniques such as ICP-OES, TEM, FT-IR, EDX, SEM, TGA, VSM, and XRD were used to characterize the structure of Fe3O4@SiO2-(Imine-Thiazole)-Cu (OAc)2 nanocomposite. To Synthesize 2-substituted benzothiazoles, the nanocomposite of Fe3O4@SiO2-(Imine-Thiazole)-Cu (OAc)2 was used as a catalyst via a one-pot three-component reaction of 2-iodoanilines, benzyl chlorides and S8. Recycling experiments revealed that a simple magnetic separation could be used to recover the copper nanocatalyst, and this nanocatalyst can be recycled eight times without any deterioration in catalytic activity.

Topics & Concepts

ThiazoleImineCatalysisChemistryNanocompositeCopperNuclear chemistryOrganic chemistryNanotechnologyMaterials scienceMulticomponent Synthesis of HeterocyclesChemical Synthesis and ReactionsSynthesis and biological activity
Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-(Imine-Thiazole)-Cu(OAc)<sub>2</sub> nanocomposite catalyzed one-pot three-component synthesis of 2-Substituted benzothiazoles using S<sub>8</sub> as sulfur source | Litcius