The rationale for the treatment of long-Covid symptoms – A cardiologist's view
Elisabeth Schieffer, Bernhard Schieffer
Abstract
The ongoing coronavirus disease 2019 pandemic left us with thousands of patients suffering from neurological, cardiovascular, and psychiatric disorders named post-acute sequelae of COVID-19 or just long-Covid . In parallel, the vaccination campaigns against SARS-CoV-2 spike protein saved millions of lives worldwide but long-Covid symptoms also appeared rarely following vaccination with a strong overlap to the “canonical” long-Covid symptoms. A therapeutic strategy targeting both, post-VAC and post-SARS-CoV-2 long-Covid symptoms is warranted since exposure to the S-protein either by vaccination or SARS-CoV-2 infection may trigger identical immuno-inflammatory cascades resulting in long-Covid symptoms.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)MedicinePandemicVaccinationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakCoronavirusIntensive care medicineDiseasePediatricsInternal medicineVirologyOutbreakInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19COVID-19 Clinical Research Studies