Radiation-induced skin injury: pathogenesis, treatment, and management
Xiaojing Yang, Hanru Ren, Xiaomao Guo, Chaosu Hu, Fu Jie
Abstract
Radiation-induced skin injury (RSI) refers to a frequently occurring complication of radiation therapy. Nearly 90% of patients having received radiation therapy underwent moderate-to-severe skin reactions, severely reducing patients' quality of life and adversely affecting their disease treatment. No gold standard has been formulated for RSIs. In the present study, the mechanism of RSI and topical medications was discussed. Besides, this study can be referenced for clinicians to treat RSIs to guide subsequent clinical medicine.
Topics & Concepts
MedicineRadiation injuryComplicationRadiation therapyRadiation exposureStandard of careIntensive care medicineSurgeryNuclear medicineEffects of Radiation ExposureChemotherapy-related skin toxicityPARP inhibition in cancer therapy