Green Esterification of Carboxylic Acids Promoted by <i>tert</i>‐Butyl Nitrite
Yonggao Zheng, Yanwei Zhao, Suyan Tao, Xingxing Li, Xionglve Cheng, Gangzhong Jiang, Xiaobing Wan
Abstract
Abstract In this work, the green esterification of carboxylic acids promoted by tert‐ butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.
Topics & Concepts
ChemistryNitriteOrganic chemistryFunctional groupAmino acidTransformation (genetics)Reaction conditionsCatalysisBiochemistryNitratePolymerGeneChemical Synthesis and ReactionsSulfur-Based Synthesis TechniquesAsymmetric Hydrogenation and Catalysis