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Safety and efficacy of elsubrutinib or upadacitinib alone or in combination (ABBV-599) in patients with rheumatoid arthritis and inadequate response or intolerance to biological therapies: a multicentre, double-blind, randomised, controlled, phase 2 trial

R. Fleischmann, Alan Friedman, Edit Drescher, Atul Singhal, Gregorio Cortes-Maisonet, Thao Doan, Wenjing Lü, Zailong Wang, Ahmed Nader, William Housley, Stanley Cohen, Peter C. Taylor, Ricardo Blanco

2022The Lancet Rheumatology13 citationsDOIOpen Access PDF

Topics & Concepts

MedicineRheumatoid arthritisJanus kinase inhibitorInternal medicinePlaceboClinical endpointRandomized controlled trialSurgeryTofacitinibPathologyAlternative medicineRheumatoid Arthritis Research and TherapiesSpondyloarthritis Studies and TreatmentsAutoimmune and Inflammatory Disorders Research
Safety and efficacy of elsubrutinib or upadacitinib alone or in combination (ABBV-599) in patients with rheumatoid arthritis and inadequate response or intolerance to biological therapies: a multicentre, double-blind, randomised, controlled, phase 2 trial | Litcius