Design, synthesis, and evaluation of anti-breast cancer activity of colchicine - combretastatin A-4 analogues containing quinoline as microtubule-targeting agents
Nam Q.H. Doan, Hoan N. Tran, Nhu T. M. Nguyen, Khang D.T. Nguyen, Vu M. Tao, Nhu N. Lai, Hương Thanh Trần, Phu H.T. Luu
Topics & Concepts
ChemistryColchicineCombretastatinQuinolineMoietyStereochemistryIC50TubulinIn silicoCytotoxicityDocking (animal)MicrotubuleBreast cancerPaclitaxelIn vitroPharmacologyBiochemistryCancerOrganic chemistryCell biologyBiologyGeneGeneticsMedicineNursingSynthesis and biological activityCancer therapeutics and mechanismsClick Chemistry and Applications