Insulin-like growth factor-1 regulates the mechanosensitivity of chondrocytes by modulating TRPV4
Nicholas Trompeter, Joseph D. Gardinier, Victor DeBarros, Mary Boggs, Vimal Gangadharan, William J. Cain, Lauren Hurd, Randall L. Duncan
Topics & Concepts
TRPV4MechanotransductionTransient receptor potential channelChondrocyteCell biologyCalcium in biologyPIEZO1ChemistryCartilageIntracellularInsulin-like growth factorActinMechanosensitive channelsStimulationGrowth factorEndocrinologyBiologyAnatomyIon channelReceptorBiochemistryExercise and Physiological ResponsesVeterinary Equine Medical ResearchIon Channels and Receptors