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Cheminformatics study of some indole compounds through QSAR modeling, ADME prediction, molecular docking, and molecular dynamic simulation to identify novel inhibitors of HCV NS5B protease

Stephen Ejeh, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen Eyije Abechi, Muhammad Tukur Ibrahim, Ramith Ramu

2023Journal of the Indian Chemical Society18 citationsDOI

Topics & Concepts

PubChemADMEChemistrySimeprevirIn silicoVirtual screeningQuantitative structure–activity relationshipDrug discoveryAutoDockSofosbuvirDocking (animal)Molecular dynamicsComputational biologyCheminformaticsHepatitis C virusMolecular descriptorStereochemistryComputational chemistryBiochemistryVirologyVirusRibavirinMedicineBiologyGeneGenotypeNursingIn vitroComputational Drug Discovery MethodsHepatitis C virus researchDiverse Scientific Research Studies
Cheminformatics study of some indole compounds through QSAR modeling, ADME prediction, molecular docking, and molecular dynamic simulation to identify novel inhibitors of HCV NS5B protease | Litcius