New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment
Yiming Xu, Dewang Jing, Dong Zhao, Yongji Wu, Lu Xing, Haroon Ur Rashid, Haodong Wang, Lisheng Wang, Hui‐Ling Cao
Topics & Concepts
MatrineHeLaChemistryMTT assayHsp90ApoptosisIC50Cell cycle checkpointStereochemistryPharmacologyCell cycleBiochemistryCellIn vitroHeat shock proteinChromatographyBiologyGeneHeat shock proteins researchBioactive Compounds and Antitumor AgentsToxin Mechanisms and Immunotoxins