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Site-Selective C<sub>sp<sup>3</sup></sub>–C<sub>sp</sub>/C<sub>sp<sup>3</sup></sub>–C<sub>sp<sup>2</sup></sub> Cross-Coupling Reactions Using Frustrated Lewis Pairs

Ayan Dasgupta, Katarína Stefkova, Rasool Babaahmadi, Brian F. Yates, Niklaas J. Buurma, Alireza Ariafard, Emma Richards, Rebecca L. Melen

2021Journal of the American Chemical Society41 citationsDOIOpen Access PDF

Abstract

cross-coupling resulted. The nature of these reaction pathways and their selectivity has been investigated by extensive electron paramagnetic resonance (EPR) studies, kinetic studies, and density functional theory (DFT) calculations both to elucidate the mechanism of these coupling reactions and to explain the solvent-dependent site selectivity.

Topics & Concepts

ChemistryLewis acids and basesSelectivityElectron paramagnetic resonanceSubstrate (aquarium)Frustrated Lewis pairDensity functional theoryAcceptorCoupling reactionCoupling (piping)SolventArylStereochemistryPhotochemistryComputational chemistryCatalysisOrganic chemistryNuclear magnetic resonanceEngineeringCondensed matter physicsGeologyPhysicsMechanical engineeringAlkylOceanographyOrganoboron and organosilicon chemistryCatalytic Cross-Coupling ReactionsRadical Photochemical Reactions
Site-Selective C<sub>sp<sup>3</sup></sub>–C<sub>sp</sub>/C<sub>sp<sup>3</sup></sub>–C<sub>sp<sup>2</sup></sub> Cross-Coupling Reactions Using Frustrated Lewis Pairs | Litcius