An electrochemical sensor based on Pt nanoparticles decorated over-oxidized polypyrrole/reduced graphene oxide nanocomposite for simultaneous determination of two neurotransmitters dopamine and 5-Hydroxy tryptamine in the presence of ascorbic acid
Kh. Ghanbari, S. Bonyadi
Abstract
In this study, the Pt nanoparticles/over-oxidized polypyrrole nanofiber/reduced graphene oxide (Pt NPs/OPPy/RGO) nanocomposite was electrochemically synthesized and used to modify a glassy carbon electrode. To confirm the Surface morphology and characterization of the nanocomposite, field emission scanning microscopy (FE-SEM), X-ray diffraction (XRD), Raman, FT-IR, and X-ray photoelectron spectroscopy (XPS) were used. Simultaneous determination of these species showed one linear response 0.1–250.0 μM and two linear responses 0.5–10.0 μM and 10.0–470.0 μM, with detection limits 42 nM and 106 nM (<i>S/N</i> = 3) for DA and 5-HT, respectively. Finally, the analytical application of this modified electrode was investigated in the human blood plasma.