Litcius/Paper detail

PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy

Duo Zhang, Albert M. Li, Guanghui Hu, Menggui Huang, Fan Yang, Lin Zhang, Kathryn E. Wellen, Xiaowei Xu, Crystal S. Conn, Wei Zou, Mark B. Kahn, Seth D. Rhoades, Aalim M. Weljie, Serge Y. Fuchs, Nduka Amankulor, Daniel Yoshor, Jiangbin Ye, Constantinos Koumenis, Yanqing Gong, Yi Fan

2023Cell Metabolism129 citationsDOIOpen Access PDF

Topics & Concepts

Cancer researchImmunotherapyChimeric antigen receptorBiologyTumor microenvironmentReprogrammingImmune systemT cellCellCell biologyImmunologyTumor cellsBiochemistryCancer, Hypoxia, and MetabolismGlioma Diagnosis and TreatmentImmune cells in cancer
PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy | Litcius