<i>In vitro</i> bioactivity evaluation of mulberry leaf extracts as nutraceuticals for the management of diabetes mellitus
Lucia Marchetti, Eleonora Truzzi, Ilaria Frosi, Adele Papetti, Silvia Cappellozza, Alessio Saviane, Federica Pellati, Davide Bertelli
Abstract
models. The results indicate that the inhibitory effect on carbohydrate digestive enzymes was likely mediated by 1-deoxynojirimycin, kaempferol, quercetin, and chlorogenic acid, acting in a synergistic way. Besides, the combined antiglycative and carbonyl trapping capacities, tested here for the first time, may help in preventing long-term complications related to AGEs in diabetic patients.
Topics & Concepts
Chlorogenic acidNutraceuticalKaempferolQuercetinDiabetes mellitusTraditional medicineCultivarFlavonoidIn vitroAntioxidantBiologyMedicineChemistryBotanyBiochemistryEndocrinologyPhytochemicals and Antioxidant ActivitiesMangiferin and Mango ExtractsNatural Antidiabetic Agents Studies