A bacteria-resistant and self-healing spray dressing based on lyotropic liquid crystals to treat infected post-operative wounds
Yue Xiao, Xuejuan Zhang, Chen Wang, Ying Huang, Ping Hu, Guanlin Wang, Yingtong Cui, Xiao Xia, Ziqiang Zhou, Xin Pan, Chuanbin Wu
Abstract
. In the infected post-operative wound model, satisfactory bacterial clearance and prominent wound healing promotion were realized by PLL-LLCP, with the survival of the bacteria at lower than 0.1% and the wound closure at higher than 90%. Thus, PLL-LLCP was believed to be an excellent candidate for the therapy of infected post-operative wounds.
Topics & Concepts
Lyotropic liquid crystalBacteriaWound healingMaterials scienceAntibioticsAntibacterial activityBacterial growthIn vivoMicrobiologyMedicineLiquid crystalSurgeryBiologyOptoelectronicsBiotechnologyGeneticsWound Healing and TreatmentsAntimicrobial agents and applicationsOcular Surface and Contact Lens