Chromophore appended DPA-based copper(<scp>ii</scp>) complexes with a diimine motif towards DNA binding and fragmentation studies
Shobhit Mathur, Kalai Selvan Karumban, Arabinda Muley, Nikhil Tuti, Unnikrishnan Paruthiyezhath Shaji, Indrajit Roy, Anushka Verma, Manoj Kumar Kumawat, Roy Anindya, Somnath Maji
Abstract
values of 1 and 2 were 43.7 μM and 18.6 μM, respectively. Our study paves the way for the designing of bio-inspired novel mixed metal complexes, which shows promising results for further exploration of molecular and mechanistic studies towards the development of non-platinum based economical metallodrugs.
Topics & Concepts
DiimineChromophoreChemistryMotif (music)CopperFragmentation (computing)DNAStereochemistryCombinatorial chemistryPhotochemistryBiochemistryBiologyOrganic chemistryCatalysisEcologyPhysicsAcousticsMetal complexes synthesis and propertiesMagnetism in coordination complexesMetal-Organic Frameworks: Synthesis and Applications