Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor
Ilian Radichev, Jeongheon Yoon, David W. Scott, Kurt Griffin, Alexei Y. Savinov
Topics & Concepts
Chimeric antigen receptorImmunologyGranzyme BBiologyAntigenAutoimmunityGranzymePancreatic isletsImmune systemCD8Granzyme AImmunotherapyCancer researchInsulinPerforinEndocrinologyIsletCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology