Low color temperature artificial lighting can slow myopia development: Long-term study using juvenile monkeys
Yingzhou Hu, 中国科学院昆明动物研究所中国科学院动物模型与人类疾病机理重点实验室, 云南 昆明 650223, 中国, Hua Yang, Hao Li, Longbao Lv, Jing Wu, Zhu Zhu, Yuhua Zhang, Fang-Fang Yan, Shuhan Fan, Shuxiao Wang, Jianping Zhao, Qiang Qi, Chang‐Bing Huang, Xintian Hu, 中国科学院昆明动物研究所国家非人类灵长类动物资源中心, 昆明动物研究所灵长类研究中心, 模式动物表型与遗传研究国家重大科技基础设施(灵长类设施), 云南 昆明 650223, 中国, 中国科学院心理研究所行为科学重点实验室, 北京 100101, 中国, 中国科学院大学心理学系, 北京 100049, 中国, 中国建筑科学研究院, 北京 100013, 中国, 中国科学院中国科学院脑科学与智能技术卓越创新中心, 上海 200031, 中国, 中国科学院半导体研究所, 北京 100083, 中国, 中国科学院大学材料科学与光电技术学院, 北京 100049, 中国, 第三代半导体材料与应用中心, 北京 100083, 中国
Abstract
The incidence of myopia has increased rapidly in recent decades, suggesting that environmental factors, such as light, may be an important cause. Correlated color temperature (CCT) is a commonly used index to quantify the spectral composition of light. Here, we used 32 juvenile monkeys (16 females and 16 males) and selected four kinds of light with typical but different CCTs to study the relationship between CCT and ocular axial elongation. After 365 days of observation, ocular axial elongation under low-CCT light was smaller than that under high-CCT light and this effect was robust and stable over the entire observation period. As excessive axial elongation is the main cause of juvenile myopia, these results provide a new approach for the prevention of juvenile myopia.