Green (cell) factories for advanced production of plant secondary metabolites
Andrey S. Marchev, Zhenya Yordanova, Milen I. Georgiev
Abstract
systems. These include metabolic engineering and CRISPR/Cas9 technology for the regulation of plant metabolism through overexpression/repression of single or multiple structural genes or transcriptional factors. The use of NMR-based metabolomics for monitoring metabolite concentrations and additionally as a tool to study the dynamics of plant cell metabolism and nutritional management is discussed here. Different types of bioreactor systems, their modification and optimal process parameters for the lab- or industrial-scale production of plant secondary metabolites are specified.
Topics & Concepts
BioproductionBioprocessBiotechnologyBiochemical engineeringMetabolic engineeringMetabolomicsPlant metabolismBiologyBiochemistryEngineeringBioinformaticsGeneEnzymePaleontologyRNATransgenic Plants and ApplicationsPlant tissue culture and regenerationMicrobial Metabolic Engineering and Bioproduction