Ablation of endothelial <i>Atg7</i> inhibits ischemia-induced angiogenesis by upregulating <i>Stat1</i> that suppresses <i>Hif1a</i> expression
Hongmin Yao, Jian Li, Zhixue Liu, Changhan Ouyang, Yu Qiu, Xiaoxu Zheng, Jing Mu, Zhonglin Xie
Abstract
knockout; VSMCs: mouse aortic smooth muscle cells; WT: wild type; ZNF148/ZFP148/ZBP-89: zinc finger protein 148.
Topics & Concepts
HIF1AAngiogenesisBiologyCell biologyAutophagyTranscription factorSTAT1Downregulation and upregulationCancer researchSignal transductionApoptosisBiochemistryGeneAutophagy in Disease and TherapyCancer-related molecular mechanisms researchMicroRNA in disease regulation