The in Situ NHC-Palladium Catalyzed Selective Activation of B(3)–H or B(6)–H Bonds of <i>o</i>-Carboranes for Hydroboration of Alkynes: An Efficient Approach to Alkenyl-<i>o</i>-carboranes
Ke Cao, Tao‐Tao Xu, Ji Wu, Caiyan Zhang, Xin‐Yu Wen, Junxiao Yang
Abstract
An in situ Pd-NHC catalyzed selective B(3,6)-H activation for hydroboration of internal alkynes has been accomplished under mild conditions. This work offers a facile approach for the synthesis of alkenyl-o-carboranes and has important reference for selective functionalization of B(3,6)–H bonds.
Topics & Concepts
HydroborationChemistryCatalysisPalladiumIn situSurface modificationMedicinal chemistryStereochemistryCombinatorial chemistryOrganic chemistryPhysical chemistryBoron Compounds in ChemistryOrganoboron and organosilicon chemistryOrthopedic Infections and Treatments