Cancer-associated fibroblasts promote migration and invasion of non-small cell lung cancer cells via METTL3-mediated RAC3 m<sup>6</sup>A modification
Mengmeng Chen, Qicheng Zhang, Sijia Zheng, Xueru Guo, Limin Cao, Yinghui Ren, Yongmei Qian, Min Wang, Xiang Wu, Ke Xu
Abstract
A modification-dependent regulation system in NSCLC metastasis, suggesting potential candidates for metastasis treatment.
Topics & Concepts
Cancer researchMetastasisStromal cellCancer-Associated FibroblastsCancer cellTumor microenvironmentCell migrationCancerGene knockdownChemistryCell biologyCellBiologyCell cultureMedicineInternal medicineTumor cellsBiochemistryGeneticsRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation