Establishment of LC-MS/MS method for determination of aloperine in rat plasma and its application in preclinical pharmacokinetics
Shengbo Huang, Yuanjin Zhang, Yanfang Zhang, Jie Liu, Zongjun Liu, Xin Wang, Xin Wang
Topics & Concepts
Formic acidChromatographyChemistryPharmacokineticsAmmonium acetateSelected reaction monitoringBioanalysisLiquid chromatography–mass spectrometryMass spectrometryPharmacologyTandem mass spectrometryHigh-performance liquid chromatographyMedicineBioactive natural compoundsSynthesis and biological activitySynthesis and bioactivity of alkaloids