Bacopa monnieri confers neuroprotection by influencing signaling pathways associated with interleukin 4, 13 and extracellular matrix organization in Alzheimer's disease: A proteomics-based perspective
Akhina Palollathil, Mohd Altaf Najar, S Amrutha, Ravishankar Pervaje, Prashant Kumar Modi, Thottethodi Subrahmanya Keshava Prasad
Abstract
altered proteins, including FOSL1, and TDO2. The protein-protein interaction network analysis of Bacopa monnieri restored proteins identified the hub gene involved in Alzheimer's disease. The findings from this study may open up new avenues for creating innovative therapeutic approaches for Alzheimer's disease.
Topics & Concepts
NeuroprotectionNeuroscienceNeuroinflammationPerspective (graphical)Signal transductionDiseaseExtracellular matrixBiologyProteomicsInterleukinCell biologyImmunologyCytokineMedicineInflammationGeneticsGeneComputer sciencePathologyArtificial intelligenceMedicinal Plants and NeuroprotectionCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatments