Tetrahydroxy stilbene glycoside ameliorates Alzheimer’s disease in APP/PS1 mice via glutathione peroxidase related ferroptosis
Yan Gao, Juntong Li, Qing-lin Wu, Shasha Wang, Songwei Yang, Xun Li, Nai‐Hong Chen, Lin Li, Lan Zhang
Topics & Concepts
Oxidative stressCell biologyGPX4NeuroinflammationProgrammed cell deathLipid peroxidationDownregulation and upregulationKEAP1PresenilinAmyloid betaReactive oxygen speciesNeuroprotectionChemistryBiologySuperoxide dismutaseBiochemistryPharmacologyAlzheimer's diseaseGlutathione peroxidaseImmunologyInflammationPeptideMedicineDiseaseApoptosisInternal medicineTranscription factorGeneFerroptosis and cancer prognosisEpigenetics and DNA MethylationRNA modifications and cancer