Accumulation of Endogenous Mutant Huntingtin in Astrocytes Exacerbates Neuropathology of Huntington Disease in Mice
Jing Liang, Siying Cheng, Yongcheng Pan, Qiong Liu, Weili Yang, Shihua Li, Xiao‐Jiang Li
Topics & Concepts
HuntingtinNeurodegenerationEndogenyMutantCell biologyBiologyHuntington's diseaseGenetically modified mouseAstrocyteHuntingtin ProteinTransgeneMolecular biologyNeuroscienceCentral nervous systemBiochemistryInternal medicineMedicineDiseaseGeneGenetic Neurodegenerative DiseasesMuscle Physiology and DisordersMitochondrial Function and Pathology