Sulfobetaine methacrylate-functionalized graphene oxide-IR780 nanohybrids aimed at improving breast cancer phototherapy
Miguel M. Leitão, Cátia G. Alves, Duarte de Melo‐Diogo, Rita Lima‐Sousa, André F. Moreira, Ilídio J. Correia
Abstract
cell studies, the combination of SBMA-functionalized GO with NIR light only reduced breast cancer cells' viability to 73%. In stark contrast, by combining IR780 loaded SBMA-functionalized GO and NIR radiation, the cancer cells' viability decreased to 20%, hence confirming the potential of this nanomaterial for cancer photothermal therapy.
Topics & Concepts
Photothermal therapyMaterials scienceGrapheneChemical engineeringSurface modificationNanotechnologyChemistryEngineeringGraphene and Nanomaterials ApplicationsNanoplatforms for cancer theranosticsNanoparticle-Based Drug Delivery