Sirt6 inhibits vascular endothelial cell pyroptosis by regulation of the Lin28b/let-7 pathway in atherosclerosis
Feng Yao, Xiaohan Lv, Zhen Jin, Danli Chen, Zihan Zheng, Jianjun Yang, Lingxuan Ren, Bo Wang, Weirong Wang, Jianyu He, Qiang Song, Jianli Gu, Rong Lin
Topics & Concepts
PyroptosisCell biologySIRT6InflammationGene knockdownEndothelial stem cellClusterinChemistryDownregulation and upregulationmicroRNATumor necrosis factor alphaBiologySirtuinCancer researchApoptosisImmunologyInflammasomeNAD+ kinaseBiochemistryIn vitroEnzymeGeneInflammasome and immune disordersBiomarkers in Disease MechanismsGout, Hyperuricemia, Uric Acid