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Placebo and Nocebo Effects

Luana Colloca, Arthur J. Barsky

2020New England Journal of Medicine632 citationsDOI

Abstract

Placebo and nocebo effects (effects of patients’ positive and negative expectations) are powerful and pervasive in clinical practice. Neurobiologic mechanisms, information offered about treatment, prior encounters with a drug or procedure, and the therapeutic milieu can all generate these effects.

Topics & Concepts

Nocebo EffectNoceboPlaceboMedicineClinical PracticeClinical trialMEDLINEIntensive care medicinePsychotherapistAlternative medicinePhysical therapyInternal medicinePsychologyPathologyLawPolitical sciencePain Management and Placebo EffectEmpathy and Medical EducationNeurology and Historical Studies
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