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O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1

Qiang Zhu, Hong Zhou, Liming Wu, Zhenyuan Lai, Didi Geng, Weiwei Yang, Jie Zhang, Zhiya Fan, Weijie Qin, Yong Wang, Ruhong Zhou, Wen Yi

2022Nature Chemical Biology107 citationsDOI

Topics & Concepts

Pancreatic cancerCell growthGlutamineMalate dehydrogenaseKRASCell biologyBiologyBiochemistryChemistryEnzymeMutationAmino acidCancerGeneGeneticsGlycosylation and Glycoproteins ResearchGalectins and Cancer BiologyProtein Tyrosine Phosphatases
O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1 | Litcius