Bis[pyrrolyl Ru( <scp>ii</scp> )] triads: a new class of photosensitizers for metal–organic photodynamic therapy
Deborah A. Smithen, Susan Monro, Mitch Pinto, John A. Roque, Roberto M. Diaz‐Rodriguez, H. Yin, Colin G. Cameron, Alison Thompson, Sherri A. McFarland
Abstract
Ten dinuclear Ru( <sc>ii</sc> ) complexes based on the bis[pyrrolyl Ru( <sc>ii</sc> )] triad scaffold were prepared to evaluate the influence of the central organic linker on the spectroscopic and <italic>in vitro</italic> photodynamic therapy (PDT) properties of the compounds.
Topics & Concepts
Photodynamic therapyChemistryMetalRutheniumCombinatorial chemistryStereochemistryMedicinal chemistryOrganic chemistryCatalysisPorphyrin and Phthalocyanine ChemistryPhotodynamic Therapy Research StudiesMetal complexes synthesis and properties