Discovery of the first ataxia telangiectasia and Rad3-related (ATR) degraders for cancer treatment
Lei Huang, Jialu Shao, Wenwen Lai, Hong‐Feng Gu, Jieping Yang, Shi Shi, Shepherd Wufoyrwoth, Zhe Song, Yi Zou, Yungen Xu, Qihua Zhu
Topics & Concepts
ChemistryAtaxia-telangiectasiaCisplatinCancer cellCell cultureCancerProteasomeCancer researchPharmacologyBiochemistryDNA damageChemotherapyDNAInternal medicineGeneticsMedicineBiologyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research