Determination of Vitamin E (α-Tocopherol Acetate) on the Surface of Human Skin by IR Fourier-Transform Spectrometry and Study of Some Aspects of Its Transdermal Transfer
I. N. Fadeikina, E. S. Peunkova, Б. К. Зуев
Abstract
Possibilities of using FTIR spectrometry for determining organic substances on the surface of human skin and studying some aspects of the transdermal transfer of cosmetic products from the surface to the inner layers of skin were considered. Vitamin E as alpha-tocopherol acetate was selected as a cosmetic product under study. A procedure for determining changes in the concentration of vitamin E over time was proposed, sampling using standard tablets of potassium bromide was used, and a dependence illustrating a decrease in the concentration of the cosmetic product over time was obtained. It was shown that FTIR spectrometry can be used as a simple and rapid method for studying mechanisms of substance transfer and transdermal properties of the skin.