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Imidazole and Derivatives Drugs Synthesis: A Review

Nidhi Rani, Randhir Singh, Praveen Kumar

2022Current Organic Synthesis32 citationsDOI

Abstract

Imidazoles have long held a special place in heterocyclic chemistry, and their derivatives have piqued interest in recent years due to their diverse chemistry and pharmacology features. Imidazole is a biologically and pharmaceutically important nitrogen-containing heterocyclic ring. As a result, researchers have been interested in imidazole molecules. For a century and a half, purine, histamine, and other natural compounds all contained the imidazole ring. A number of imidazole drugs have been prepared and marketed for the treatment of various diseases. In view of this, we herein report a detailed account of synthetic procedures for various imidazole drugs.

Topics & Concepts

ImidazoleChemistryRing (chemistry)Combinatorial chemistryPurineOrganic chemistryEnzymeSynthesis of heterocyclic compoundsChemical Synthesis and AnalysisSynthesis and Biological Evaluation
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