Plasmid-Mediated Ciprofloxacin Resistance Imparts a Selective Advantage on Escherichia coli ST131
Minh-Duy Phan, Kate M. Peters, Laura Alvarez Fraga, Steven C. Wallis, Steven J. Hancock, Nguyen Thi Khanh Nhu, Brian M. Forde, Michelle J. Bauer, David L. Paterson, Scott A. Beatson, Jeffrey Lipman, Mark A. Schembri
Abstract
Escherichia coli ST131 is a recently emerged antibiotic resistant clone responsible for high rates of urinary tract and bloodstream infections. Despite its global dominance, the precise mechanisms that have driven the rapid dissemination of ST131 remain unknown.
Topics & Concepts
Escherichia coliMicrobiologyCiprofloxacinBiologyAntibioticsGeneAntibiotic resistanceEnterobacteriaceaeclone (Java method)Multiple drug resistanceBacteriaDrug resistanceBacterial geneticsEscherichia coli ProteinsAntibacterial agentCarbapenemPlasmidEnzymeAntibiotic Resistance in BacteriaEscherichia coli research studiesUrinary Tract Infections Management