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The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives

Stefano Iotti, Federica I. Wolf, Andrzej Mazur, Jeanette A.M. Maier

2020Magnesium Research85 citationsDOIOpen Access PDF

Abstract

More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common, might foment the transition from mild to critical clinical manifestations of the disease. Epidemiological, clinical, and fundamental research is needed to clarify the potential role of Mg deficiency in COVID-19.

Topics & Concepts

PathogenesisPandemicCoronavirus disease 2019 (COVID-19)DiseaseEpidemiologyMedicineEndothelial dysfunctionImmunologyInternal medicineInfectious disease (medical specialty)Magnesium in Health and DiseaseParathyroid Disorders and TreatmentsBiomarkers in Disease Mechanisms
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