EZH2 is associated with cartilage degeneration in osteoarthritis by promoting SDC1 expression via histone methylation of the microRNA-138 promoter
Jian Wang, Xiang Wang, Xu Ding, Tao Huang, Dengxin Song, Hairong Tao
Topics & Concepts
EZH2EpigeneticsCartilagemicroRNABiologySyndecan 1Histone methylationDNA methylationCell biologyCancer researchChemistryGene expressionCellBiochemistryGeneAnatomyCancer-related molecular mechanisms researchOsteoarthritis Treatment and MechanismsMicroRNA in disease regulation