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Genome Sequencing of Wastewater Confirms the Arrival of the SARS-CoV-2 Omicron Variant at Frankfurt Airport but Limited Spread in the City of Frankfurt, Germany, in November 2021

Shelesh Agrawal, Laura Orschler, Simona Tavazzi, Robert Greither, Bernd Manfred Gawlik, Susanne Lackner

2022Microbiology Resource Announcements67 citationsDOIOpen Access PDF

Abstract

Wastewater-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surveillance of Frankfurt Airport by genome sequencing was used to detect SARS-CoV-2 variants entering the region. In November 2021, we found all characteristic mutations of Omicron in wastewater originating from Frankfurt Airport before the first confirmed clinical report from an arriving passenger on 26 November 2021.

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Wastewater2019-20 coronavirus outbreakWhole genome sequencingBiologyVirologyGenomeGeneticsMedicineEnvironmental scienceGeneEnvironmental engineeringOutbreakInfectious disease (medical specialty)Internal medicineDiseaseSARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchBiosensors and Analytical Detection